Regis O'Keefe

Orthopaedic Surgery Physician · Saint Louis, MO

About Regis O'Keefe

I am Dr. Regis James O'Keefe, MD, an orthopedic surgeon dedicated to providing expert care for musculoskeletal conditions and injuries. My specialty lies in musculoskeletal oncology and adult reconstructive surgery of the hip and knee.

Throughout my practice, I focus on treating a wide range of conditions, including benign and malignant bone tumors, soft tissue tumors, infections, and skeletal reconstruction. I also specialize in sports injury care, degenerative diseases, birth defects, joint repair, and replacement surgeries.

As a board-certified orthopedic surgeon in St. Louis, Missouri, I have the privilege of working at reputable institutions such as Barnes-Jewish Hospital and St. Louis Children's Hospital. My goal is to deliver compassionate and personalized care to patients of all ages, helping them achieve optimal recovery and wellness.

Education and training

Office

4921 PARKVIEW PL · Saint Louis, MO 63110-1032

Record updated 2026-07-11 — verified against the NPI registry (NPPES/CMS) and OpenDoc's continuous accuracy loops.

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